Xi'an LiSun Biological Technology Co. Ltd.

Berberine hydrochloride is an isoquinoline alkaloid isolated from a variety of Chinese herbs, including Coptidis rhizoma, Phellodendron chinense schneid, and Phellodendron amurense, and has diverse pharmacological actions. It has antidiabetic and antilipid peroxidation activity, as well as an anti-atherosclerotic action, and also has neuroprotective properties and improves polycystic ovary syndrome.1–5 Berberine hydrochloride is widely used as an antibacterial, antifungal, and anti-inflammatory product, and has been used as a gastrointestinal remedy for thousands of years in China.

Synonym: Berberine hydrochloride

Chemical name: BERBERINE HCL, 5,6-DIHYDRO-9,10-DIMETHOXY-BENZO[G]-1,3-BENZODIOXOLO[5,6-A]QUINOLIZINIUM, CHLORIDE, BERBERINE CHLORIDE

Molecular Formula: C20H18ClNO4;Formula Weight:371.81

CAS NO.: 633-65-8

Physical Property: hydroxyl compound is yellow needle crystalline (aether);

M.P.: 145℃; dehydration of chloride is yellow crystalline; slightly soluble in cold water, freely soluble in hot water, practically insoluble in ethanol, chloroform; iodide M.P.: 263-265℃(disassembled).

Item	Specification
Assay by HPLC	≥97%
Appearance	Yellow crystalline powder
Odor	Characteristic
Particle size	100% pass through US standard Sieve # 80 mesh
Bulk density	≥0.30 gm/cc
Tapped density	≥0.50 gm/cc
Identification (A,B,C,D,E)	Must positive
Other alkaloid	Complied
Heavy metals	≤10 ppm
--Arsenic	≤1 ppm
--Mercury	≤0.1 ppm
--Cadmium	≤1 ppm
--Lead	≤3 ppm
Ashes	≤0.2%
Loss on Drying	≤12.0%
Total Plate Count	≤1000 cfu/g
Total Yeast & Mildew	≤100 cfu/g
Coliforms	≤10 cfu/g
E.Coli	Negative
Salmonella	Negative

Main function

- Removing heat and damp, relieving fire and eliminating toxins;
- Relaxing vascular smooth muscle and exciting other smooth muscle, such as bladder muscle, bronchial muscle and gastrointestinal muscel;
- Antimicrobial and antibacterial;
- Treatment of bacillary dysentery, pulmonary abscess, brucellosis, acute tonsillitis, maxillary sinusitis, oral and maxillofacial inflammation embolism.